Polypharmacy Guidance: appropriate prescribing, making medicines safe, effective and sustainable 2025 - 2028

Closes 22 Sep 2025

11. Constipation

Constipation is typically defined as bowel motions less than three times a week. Constipation is a common symptom and can be short term or chronic, if lasting three months or more.

  • Provide information on first line evidence based dietary advice
  • Many medicines are implicated in inducing constipation, including those with high anticholinergic burden. Such medication should be reviewed and stopped or reduced where appropriate.
  • People prescribed multiple laxatives should be reviewed
  • Education is key in helping individuals understand why multiple laxatives are not recommended long-term
  • Consider step-wise approach to reducing/stopping laxatives
11a. Do you agree or disagree with the recommendations for management of constipation?
11b. Please provide any further comments about our recommendations.